2005–06 Clemson Tigers women's basketball team

The 2005–06 Clemson Tigers women's basketball team represented Clemson University during the 2005–06 NCAA Division I women's basketball season. The Tigers were led by first year head coach Cristy McKinney. The Tigers, members of the Atlantic Coast Conference, played their home games at Littlejohn Coliseum.

Schedule
!colspan=9 style=""| ACC Tournament