2010 Abierto Internacional del Bicentenario Leon – Singles

Dick Norman was the defending champion, but chose to compete in Monte Carlo instead. Santiago González won in the final 3–6, 6–1, 7–5 against Michał Przysiężny.

Seeds
• # 🇵🇱 Michał Przysiężny (final)

• # 🇦🇺 Greg Jones (semifinals)

• # 🇩🇪 Andre Begemann (second round)

• # 🇮🇳 Prakash Amritraj (quarterfinals)

• # 🇺🇸 Lester Cook (quarterfinals)

• # 🇲🇽 Santiago González (champion)

• # 🇮🇪 Conor Niland (second round)

• # 🇰🇷 Im Kyu-tae (quarterfinals)