2010 Aspria Tennis Cup – Singles

Alessio di Mauro was the defending champion, but he lost in the first round against Mikhail Kukushkin in the first round.

Frederico Gil won in the final 6–1, 7–5 against Máximo González.

Seeds
• # Frederico Gil (champion)

• # 🇮🇹 Filippo Volandri (first round)

• # 🇰🇿 Mikhail Kukushkin (quarterfinals)

• # 🇪🇸 Rubén Ramírez Hidalgo (semifinals)

• # 🇪🇸 Alberto Martín (second round)

• # 🇪🇸 Pablo Andújar (second round)

• # 🇦🇷 Federico Delbonis (second round)

• # 🇷🇴 Adrian Ungur (quarterfinals, retired)