2010 Concurso Internacional de Tenis – San Sebastián – Singles

Thiemo de Bakker was the defending champion but chose to compete in Cincinnati Masters instead. Albert Ramos-Viñolas won in the final defeating Benoît Paire 6–4, 6–2.

Seeds
• # 🇪🇸 Pere Riba (first round)

• # 🇪🇸 Rubén Ramírez Hidalgo (semifinals)

• # 🇪🇸 Pablo Andújar (first round)

• # 🇩🇪 Julian Reister (semifinals)

• # 🇪🇸 Santiago Ventura (second round)

• # 🇰🇿 Yuri Schukin (first round, retired)

• # 🇪🇸 Albert Ramos-Viñolas (champion)

• # 🇩🇪 Denis Gremelmayr (second round, retired)