2012–13 UC Sampdoria season

The 2012–13 season was Sampdoria's 66th in existence. Sampdoria finished the 2011–12 season in sixth place in Serie B and were promoted to Serie A through the play-offs.

Appearances and goals
! colspan="10" style="background:#dcdcdc; text-align:center"| Goalkeepers

! colspan="10" style="background:#dcdcdc; text-align:center"| Defenders

! colspan="10" style="background:#dcdcdc; text-align:center"| Midfielders

! colspan="10" style="background:#dcdcdc; text-align:center"| Forwards

! colspan="10" style="background:#dcdcdc; text-align:center"| Players transferred out during the season

Top scorers
This includes all competitive matches. The list is sorted by shirt number when total goals are equal. {| class="wikitable sortable" style="font-size: 95%; text-align: center;" !width=15|R !width=15|No. !width=15|Pos !width=15|Nat !width=150|Name !width=80|Serie A !width=80|Coppa Italia !width=80|Total
 * 1
 * 98
 * FW
 * 🇦🇷
 * Mauro Icardi
 * 10
 * 0
 * 10
 * 2
 * 23
 * FW
 * 🇧🇷
 * Éder
 * 7
 * 0
 * 7
 * 3
 * 10
 * FW
 * 🇦🇷
 * Maxi López
 * 4
 * 1
 * 5
 * 4
 * 6
 * MF
 * 🇮🇹
 * Enzo Maresca
 * 3
 * 0
 * 3
 * 11
 * MF
 * 🇮🇹
 * Gianni Munari
 * 3
 * 0
 * 3
 * 16
 * MF
 * 🇮🇹
 * Andrea Poli
 * 3
 * 0
 * 3
 * 7
 * Own goals
 * 2
 * 0
 * 2
 * 2
 * MF
 * Marcelo Estigarribia
 * 2
 * 0
 * 2
 * 12
 * FW
 * 🇮🇹
 * Gianluca Sansone
 * 2
 * 0
 * 2
 * 19
 * DF
 * 🇮🇹
 * Lorenzo De Silvestri
 * 2
 * 0
 * 2
 * 11
 * 3
 * DF
 * 🇮🇹
 * Andrea Costa
 * 1
 * 0
 * 1
 * 9
 * FW
 * 🇮🇹
 * Nicola Pozzi
 * 1
 * 0
 * 1
 * 14
 * MF
 * 🇪🇸
 * Pedro Obiang
 * 1
 * 0
 * 1
 * 25
 * MF
 * 🇷🇸
 * Nenad Krstičić
 * 1
 * 0
 * 1
 * 28
 * DF
 * 🇮🇹
 * Daniele Gastaldello
 * 1
 * 0
 * 1
 * 1
 * 14
 * MF
 * 🇪🇸
 * Pedro Obiang
 * 1
 * 0
 * 1
 * 25
 * MF
 * 🇷🇸
 * Nenad Krstičić
 * 1
 * 0
 * 1
 * 28
 * DF
 * 🇮🇹
 * Daniele Gastaldello
 * 1
 * 0
 * 1
 * DF
 * 🇮🇹
 * Daniele Gastaldello
 * 1
 * 0
 * 1