2012 Seguros Bolívar Open Cali – Singles

Alejandro Falla was the defending champion, but retired from his first round match. João Souza won the title, defeating Thiago Alves 6–2, 6–4 in the final.

Seeds
• # 🇨🇴 Santiago Giraldo (second round, withdrew because of peritonitis surgery)

• # 🇨🇴 Alejandro Falla (first round, retired)

• # 🇪🇸 Rubén Ramírez Hidalgo (quarterfinals)

• # 🇺🇸 Wayne Odesnik (quarterfinals)

• # 🇧🇷 Thiago Alves (final)

• # 🇦🇷 Martín Alund (semifinals)

• # 🇦🇷 Guido Pella (quarterfinals)

• # 🇧🇷 João Souza (champion)