2012 Seguros Bolívar Open Medellín – Singles

Víctor Estrella was the defending champion but did not participate. Paolo Lorenzi defeated Leonardo Mayer 7–6(7–5), 6–7(4–7), 6–4 in the final to win the title.

Seeds
• # 🇦🇷 Leonardo Mayer (final)

• # 🇮🇹 Paolo Lorenzi (champion)

• # 🇪🇸 Rubén Ramírez Hidalgo (second round)

• # 🇦🇷 Martín Alund (first round)

• # 🇧🇷 João Souza (quarterfinals)

• # Frederico Gil (quarterfinals)

• # 🇺🇸 Wayne Odesnik (quarterfinals)

• # Jorge Aguilar (first round)