2013 Soweto Open – Men's singles

The defending champion from 2011 was Izak van der Merwe, as there was no event in 2012. He is not entered in this year's event. Vasek Pospisil defeated Michał Przysiężny while leading 6–7(7–9), 6–0, 4–1 in the final before Przysiężny retired.

Seeds
• # 🇸🇰 Lukáš Lacko (semifinals)

• # 🇺🇸 Rajeev Ram (quarterfinals)

• # 🇨🇦 Vasek Pospisil (champion)

• # 🇵🇱 Michał Przysiężny (final, retired)

• # 🇩🇪 Dustin Brown (quarterfinals)

• # 🇧🇷 Thiago Alves (second round)

• # Rik de Voest (quarterfinals)

• # 🇧🇷 Fabiano de Paula (second round)