2015–16 Eastern Illinois Panthers men's basketball team

The 2015–16 Eastern Illinois Panthers men's basketball team represented Eastern Illinois University during the 2015–16 NCAA Division I men's basketball season. The Panthers, led by fourth-year head coach Jay Spoonhour, played their home games at Lantz Arena and were members of the West division of the Ohio Valley Conference. They finished the season 13–17, 9–7 in OVC play, to finish in third place in the West division. They lost in the first round of the OVC tournament to Murray State.

Previous season
The Panthers finished the 2014–15 season 18–15, 9–7 in OVC play, to finish in third place in the West division. They advanced to the quarterfinals of the OVC tournament where they lost to Belmont. They were invited to the CollegeInsider.com Tournament where they defeated Oakland in the first round before losing in the second round to Evansville.

Schedule
Source:

!colspan=9 style=| Exhibition

!colspan=9 style=| Regular season

!colspan=9 style=|Ohio Valley tournament