2015–16 Nicholls State Colonels women's basketball team

The 2015–16 Nicholls State Colonels women's basketball team represented Nicholls State University during the 2015–16 NCAA Division I women's basketball season. The Colonels, led by eighth year head coach DoBee Plaisance, played their home games at Stopher Gym and were members of the Southland Conference. They finished the season 10–19, 8–10 in Southland play to in seventh place. They lost in the first round of the Southland women's tournament to Sam Houston State.

Schedule
!colspan=9 style=";"| Non-conference regular season

!colspan=9 style=";"| Southland Conference regular season

!colspan=9 style=";"| Southland Conference tournament

Source