2016 Aegon Manchester Trophy – Singles

Sam Groth was the defending champion, but lost in the quarterfinals to Denis Kudla.

Dustin Brown won the title after defeating Lu Yen-hsun 7–6(7–5), 6–1 in the final.

Seeds
• # 🇺🇸 Denis Kudla (semifinals)

• # 🇺🇸 Rajeev Ram (first round)

• # 🇬🇧 Daniel Evans (first round)

• # Lu Yen-hsun (final)

• # 🇩🇪 Benjamin Becker (first round)

• # 🇺🇦 Sergiy Stakhovsky (quarterfinals)

• # 🇦🇺 Sam Groth (quarterfinals)

• # 🇺🇸 Bjorn Fratangelo (withdrew)