2016 Città di Como Challenger – Singles

Andrey Kuznetsov was the defending champion but chose not to defend his title.

Kenny de Schepper won the title after defeating Marco Cecchinato 2–6, 7–6(7–0), 7–5 in the final.

Seeds
• # 🇦🇹 Gerald Melzer (quarterfinals)

• # 🇪🇸 Roberto Carballés Baena (first round)

• # 🇯🇵 Taro Daniel (semifinals)

• # 🇸🇰 Andrej Martin (first round)

• # 🇦🇷 Marco Trungelliti (second round)

• # 🇦🇷 Leonardo Mayer (quarterfinals)

• # 🇪🇸 Albert Montañés (second round)

• # 🇮🇹 Marco Cecchinato (final)