2016 Empire Slovak Open – Singles

Danka Kovinić was the defending champion, but chose to participate in Rome instead.

Kateřina Siniaková won the title, defeating Anastasija Sevastova in the final, 7–6(7–4), 5–7, 6–0.

Seeds
• # 🇸🇰 Magdaléna Rybáriková (first round, retired)

• # 🇹🇷 Çağla Büyükakçay (second round)

• # Anastasija Sevastova (final)

• # 🇰🇿 Zarina Diyas (semifinals)

• # 🇨🇿 Kristýna Plíšková (quarterfinals)

• # 🇵🇱 Magda Linette (second round)

• # Stefanie Vögele (withdrew)

• # 🇷🇴 Andreea Mitu (first round)