2016 Karshi Challenger – Singles

Teymuraz Gabashvili was the defending champion but chose not to participate.

Marko Tepavac won the title after defeating Dudi Sela 2–6, 6–3, 7–6(7–4) in the final.

Seeds
• # 🇮🇱 Dudi Sela (final)

• # 🇷🇺 Karen Khachanov (quarterfinals)

• # 🇲🇩 Radu Albot (semifinals)

• # 🇰🇿 Aleksandr Nedovyesov (second round)

• # 🇮🇱 Amir Weintraub (first round)

• # 🇺🇦 Denys Molchanov (first round)

• # 🇰🇿 Dmitry Popko (quarterfinals)

• # 🇷🇺 Aslan Karatsev (second round)