2016 Pekao Szczecin Open – Singles

Jan-Lennard Struff was the defending champion but chose not to participate.

Alessandro Giannessi won the title after defeating Dustin Brown 6–2, 6–3 in the final.

Seeds
• # 🇪🇸 Marcel Granollers (first round, retired)

• # 🇪🇸 Íñigo Cervantes (second round)

• # 🇩🇪 Dustin Brown (final)

• # 🇲🇩 Radu Albot (first round)

• # Nikoloz Basilashvili (first round)

• # 🇷🇺 Teymuraz Gabashvili (first round)

• # 🇪🇸 Albert Montañés (quarterfinals, retired)

• # 🇮🇹 Marco Cecchinato (quarterfinals)