2016 Tilia Slovenia Open – Singles

Luca Vanni was the defending champion but chose not to defend his title.

Florian Mayer won the title after defeating Daniil Medvedev 6–1, 6–2 in the final.

Seeds
• # 🇩🇪 Florian Mayer (champion)

• # 🇦🇷 Renzo Olivo (quarterfinals)

• # 🇸🇰 Jozef Kovalík (second round)

• # Grega Žemlja (semifinals)

• # 🇩🇪 Peter Gojowczyk (withdrew)

• # 🇭🇺 Márton Fucsovics (quarterfinals)

• # 🇷🇺 Alexander Kudryavtsev (semifinals)

• # 🇧🇪 Ruben Bemelmans (second round)