2018 Fuzion 100 Manchester Trophy – Singles

Zarina Diyas was the defending champion, but chose to participate in Nottingham instead.

Ons Jabeur won the title, defeating Sara Sorribes Tormo in the final, 6–2, 6–1.

Seeds
• # 🇺🇸 Jennifer Brady (first round)

• # 🇹🇭 Luksika Kumkhum (second round)

• # Viktorija Golubic (quarterfinals)

• # 🇺🇸 Nicole Gibbs (second round)

• # 🇪🇸 Sara Sorribes Tormo (final)

• # 🇷🇺 Evgeniya Rodina (semifinals)

• # 🇬🇧 Naomi Broady (first round)

• # 🇮🇹 Jasmine Paolini (first round)