2018 LTP Charleston Pro Tennis – Singles

Madison Brengle was the defending champion but lost in the final to Taylor Townsend, 0–6 4–6.

Seeds
• # 🇺🇸 Madison Brengle (final)

• # 🇺🇸 Taylor Townsend (champion)

• # 🇨🇴 Mariana Duque Mariño (second round)

• # 🇺🇸 Nicole Gibbs (second round)

• # 🇺🇸 Kristie Ahn (first round)

• # 🇺🇦 Anhelina Kalinina (second round)

• # 🇺🇸 Jamie Loeb (quarterfinals)

• # 🇺🇸 Irina Falconi (quarterfinals)