2018 Mercer Tennis Classic – Singles

Anna Karolína Schmiedlová was the defending champion, but chose to compete in Poitiers instead.

Varvara Lepchenko won the title, defeating Verónica Cepede Royg in the final, 6–4, 6–4.

Seeds
• # 🇺🇸 Madison Brengle (first round)

• # 🇺🇸 Jessica Pegula (quarterfinals)

• # 🇷🇺 Sofya Zhuk (first round)

• # 🇺🇸 Claire Liu (first round)

• # 🇺🇸 Nicole Gibbs (first round)

• # 🇺🇸 Kristie Ahn (first round)

• # 🇨🇿 Marie Bouzková (semifinals, retired)

• # 🇺🇸 Christina McHale (first round)