2018 Open de Guadeloupe – Singles

Malek Jaziri was the defending champion but chose not to defend his title.

Dušan Lajović won the title after defeating Denis Kudla 6–4, 6–0 in the final.

Seeds
• # Stefanos Tsitsipas (second round)

• # Gastão Elias (second round)

• # 🇷🇸 Dušan Lajović (champion)

• # 🇧🇪 Ruben Bemelmans (semifinals)

• # 🇨🇦 Peter Polansky (second round)

• # 🇺🇸 Denis Kudla (final)

• # 🇫🇷 Calvin Hemery (quarterfinals)

• # 🇺🇸 Bradley Klahn (quarterfinals)