2020–21 En Avant Guingamp season

The 2020–21 En Avant Guingamp season was the club's 108th season in existence and its second consecutive season in the second division of French football. In addition to the domestic league, Guingamp participated in this season's edition of the Coupe de France. The season covered the period from 1 July 2020 to 30 June 2021.

Matches
The league fixtures were announced on 9 July 2020.