2020–21 NCAA Division II football season

The 2020–21 NCAA Division II football season was the component of the 2020 college football season organized by the NCAA at the Division II level in the United States. Due to the COVID-19 pandemic, only a few games were played during the traditional fall season. For other teams that chose to play during the 2020–21 school year, the regular season began on February 27, 2021, and culminated on April 25.

The season concluded with the end of the regular season, as the playoffs and championship game were not held due to the pandemic.

D-II team wins over FCS teams

 * November 7, 2020: 34, Abilene Christian 21
 * April 1, 2021: 21, Tarleton State 14

Conference standings
Only four conferences (GLVC, G-MAC, Mountain East and SAC) and two independents (Barton and Erskine) decided to play the season. All of them played a spring schedule. GAC, GLIAC, GNAC, Gulf South, Lone Star, MIAA, PSAC, RMAC and SIAC cancelled their football season, but some of their teams decided to play. Standings do not count games designated as exhibitions/scrimmages, only games in a school's official statistics.

Conferences that did not play
The following conferences did not hold a football season in fall 2020 or spring 2021, and none of their members opted to play independently.
 * Central Intercollegiate Athletic Association – announced on October 2, 2020, that the football season would not be played.
 * Northeast-10 Conference – announced on January 13, 2021, that postponed fall sports would not be rescheduled for the spring.
 * Northern Sun Intercollegiate Conference – did not have a football season.