2021–22 FIBA Europe Cup Play-offs

The 2021–22 FIBA Europe Cup play-offs began on 9 March and concluded on 20 and 27 April 2022 with the 2022 FIBA Europe Cup Finals, decided the champions of the 2021–22 FIBA Europe Cup. A total of eight teams competed in the play-offs.

Format
Each tie in the knockout phase, was played over two legs, with each team playing one leg at home.

Quarterfinals
The first legs were played on 9 and 10 March 2022, and the second legs were played on 16 March 2022. 


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Semifinals
The first legs were played on 30 March 2022, and the second legs were played on 6 April 2022. 


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Finals
The first leg was played on 20 April 2022, and the second legs was played on 27 April 2022. 


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