2021–22 Grand Canyon Antelopes men's basketball team

The 2021–22 Grand Canyon Antelopes men's basketball team represented Grand Canyon University during the 2021–22 NCAA Division I men's basketball season. They were led by head coach Bryce Drew in his second season. The Antelopes played their home games at GCU Arena in Phoenix, Arizona as members of the Western Athletic Conference.

Previous season
The 2020–21 Antelopes won the WAC regular-season championship and the 2021 WAC men's basketball tournament. The 2020–21 team is the first-ever Grand Canyon team to be selected for March Madness, being selected as a 15-seed in the West region for the 2021 NCAA Division I men's basketball tournament, where they lost to Iowa in the first round.

Schedule and results
!colspan=12 style=| Exhibition

!colspan=12 style=| Non-conference regular season

!colspan=12 style=| WAC Conference Season

!colspan=9 style=|WAC tournament

Source