2021 Engie Open Saint-Gaudens Occitanie – Singles

Anna Kalinskaya was the defending champion having won the previous edition in 2019, but chose not to participate.

Clara Burel won the title, defeating Alexandra Dulgheru in the final, 6–2, 1–6, 6–2.

Seeds
• # Viktorija Golubic (semifinals)

• # 🇫🇷 Océane Dodin (first round)

• # 🇸🇰 Kristína Kučová (quarterfinals)

• # 🇯🇵 Kurumi Nara (quarterfinals)

• # 🇦🇹 Barbara Haas (quarterfinals)

• # 🇫🇷 Harmony Tan (withdrew)

• # 🇫🇷 Clara Burel (champion)

• # 🇪🇸 Cristina Bucșa (first round)

• # 🇷🇴 Elena-Gabriela Ruse (second round)