2021 Kyiv Open – Singles

This was the first edition of the tournament.

Franco Agamenone won the title after defeating Sebastián Báez 7–5, 6–2 in the final.

Seeds
• # 🇦🇷 Sebastián Báez (final)

• # Frederico Ferreira Silva (first round)

• # 🇫🇷 Quentin Halys (first round)

• # 🇰🇿 Dmitry Popko (quarterfinals, retired)

• # 🇬🇧 Jay Clarke (first round)

• # 🇺🇦 Sergiy Stakhovsky (second round)

• # 🇫🇷 Constant Lestienne (first round)

• # 🇫🇷 Tristan Lamasine (second round)