2021 Tampere Open – Singles

Mikael Ymer was the defending champion but chose not to defend his title.

Jiří Lehečka won the title after defeating Nicolás Kicker 5–7, 6–4, 6–3 in the final.

Seeds
• # Botic van de Zandschulp (semifinals)

• # Henri Laaksonen (withdrew)

• # 🇫🇷 Antoine Hoang (first round)

• # 🇪🇸 Mario Vilella Martínez (quarterfinals)

• # 🇰🇿 Dmitry Popko (quarterfinals)

• # 🇧🇪 Kimmer Coppejans (first round)

• # 🇫🇷 Alexandre Müller (second round)

• # 🇦🇷 Guido Andreozzi (second round)