2022–23 UEFA Europa Conference League knockout phase

The 2022–23 UEFA Europa Conference League knockout phase began on 16 February with the knockout round play-offs and ended on 7 June 2023 with the final at the Fortuna Arena in Prague, Czech Republic, to decide the champions of the 2022–23 UEFA Europa Conference League. A total of 24 teams competed in the knockout phase.

Times are CET/CEST, as listed by UEFA (local times, if different, are in parentheses).

Qualified teams
The knockout phase involved 24 teams: the 16 teams which qualified as winners and runners-up of each of the eight groups in the group stage, and the eight third-placed teams from the Europa League group stage.

Format
Each tie in the knockout phase, apart from the final, was played over two legs, with each team playing one leg at home. The team that scored more goals on aggregate over the two legs advanced to the next round. If the aggregate score was level, then 30 minutes of extra time were played (the away goals rule was not applied). If the score was still level at the end of extra time, the winners were decided by a penalty shoot-out. In the final, which was played as a single match, if the score was level at the end of normal time, extra time would be played, followed by a penalty shoot-out if the score was still level.  The mechanism of the draws for each round was as follows:
 * In the draw for the knockout round play-offs, the eight group runners-up were seeded, and the eight Europa League group third-placed teams were unseeded. The seeded teams were drawn against the unseeded teams, with the seeded teams hosting the second leg. Teams from the same association could not be drawn against each other.
 * In the draw for the round of 16, the eight group winners were seeded, and the eight winners of the knockout round play-offs were unseeded. Again, the seeded teams were drawn against the unseeded teams, with the seeded teams hosting the second leg. Teams from the same association could not be drawn against each other.
 * In the draws for the quarter-finals and semi-finals, there were no seedings, and teams from the same association could be drawn against each other. As the draws for the quarter-finals and semi-finals were held together before the quarter-finals were played, the identity of the quarter-final winners was not known at the time of the semi-final draw. A draw was also held to determine which semi-final winner would be designated as the "home" team for the final (for administrative purposes as it was played at a neutral venue).

In the knockout phase, teams from the same or nearby cities (Roma and Lazio, Fenerbahçe and İstanbul Başakşehir, and Anderlecht and Union SG, who share the same stadium), the first team listed played in the Europa League were not scheduled to play at home on the same day, due to logistics and crowd control. To avoid such scheduling conflicts, adjustments had to be made by UEFA. For the knockout round playoffs and a round of 16, since both teams were drawn to play at home in a given leg, the home match of the team that was not the domestic cup or Europa Conference League winner, or lower domestic ranking (if neither are the domestic cup or Europa Conference League winner; i.e. Lazio and Anderlecht for this season), was moved from Thursday to Wednesday. For the quarter-finals and semi-finals, if the two teams were drawn to play at home for the same leg, the order of legs of the tie involving the team with the lowest priority was reversed from the original draw.

Schedule
The schedule was as follows (all draws were held at the UEFA headquarters in Nyon, Switzerland).

Bracket


Knockout round play-offs
 The draw for the knockout round play-offs was held on 7 November 2022, 14:00 CET. 

Summary
 The first legs were played on 16 February, and the second legs were played on 23 February 2023.


 * }

Matches
''1–1 on aggregate. Gent won 5–3 on penalties.''

Basel won 2–1 on aggregate.

Lazio won 1–0 on aggregate.

Lech Poznań won 1–0 on aggregate.

Fiorentina won 7–2 on aggregate.

AEK Larnaca won 1–0 on aggregate.

Sheriff Tiraspol won 3–2 on aggregate.

''2–2 on aggregate. Anderlecht won 3–0 on penalties.''

Round of 16
 The draw for the round of 16 was held on 24 February 2023, 13:00 CET. 

Summary
 The first legs were played on 7 and 9 March, and the second legs were played on 15 and 16 March 2023.


 * }

Matches
West Ham United won 6–0 on aggregate.

Fiorentina won 5–1 on aggregate.

AZ won 4–2 on aggregate.

Lech Poznań won 5–0 on aggregate.

''4–4 on aggregate. Basel won 4–1 on penalties.''

Nice won 4–1 on aggregate.

Anderlecht won 2–1 on aggregate.

Gent won 5–2 on aggregate.

Quarter-finals
 The draw for the quarter-finals was held on 17 March 2023, 14:00 CET. 

Summary
 The first legs were played on 13 April, and the second legs were played on 20 April 2023.

Notes 
 * }

Matches
Fiorentina won 6–4 on aggregate.

West Ham United won 5–2 on aggregate.

''2–2 on aggregate. AZ won 4–1 on penalties.''

Basel won 4–3 on aggregate.

Semi-finals
<section begin=SF /> The draw for the semi-finals was held on 17 March 2023, 14:00 CET, after the quarter-final draw. <section end=SF />

Summary
<section begin=SF /> The first legs were played on 11 May, and the second legs were played on 18 May 2023.


 * }<section end=SF />

Matches
Fiorentina won 4–3 on aggregate.

West Ham United won 3–1 on aggregate.

Final
<section begin=F />

The final was played on 7 June 2023 at the Fortuna Arena in Prague. A draw was held on 17 March 2023, after the quarter-final and semi-final draws, to determine the "home" team for administrative purposes. <section end=F />