2022 FIFA World Cup qualification – UEFA Group E

The 2022 FIFA World Cup qualification UEFA Group E was one of the ten UEFA groups in the World Cup qualification tournament to decide which teams would qualify for the 2022 FIFA World Cup finals tournament in Qatar. Group E consisted of five teams: Belarus, Belgium, the Czech Republic, Estonia and Wales. The teams played against each other home-and-away in a round-robin format.

The group winners, Belgium, qualified directly for the World Cup finals, while the runners-up, Wales, and the third-placed team, the Czech Republic, advanced to the second round (play-offs).

Matches
The fixture list was confirmed by UEFA on 8 December 2020, the day following the draw. Times are CET/CEST, as listed by UEFA (local times, if different, are in parentheses).

Discipline
A player was automatically suspended for the next match for the following offences: The following suspensions were served during the qualifying matches:
 * Receiving a red card (red card suspensions could be extended for serious offences)
 * Receiving two yellow cards in two different matches (yellow card suspensions were carried forward to the play-offs, but not the finals or any other future international matches)