2022 Trofeo Faip–Perrel – Singles

Holger Rune was the defending champion but chose not to defend his title.

Otto Virtanen won the title after defeating Jan-Lennard Struff 6–2, 7–5 in the final. It was his first Challenger title, and he did not drop a single set en route to the title.

Seeds
• # 🇵🇱 Kamil Majchrzak (first round)

• # Nuno Borges (semifinals)

• # 🇨🇳 Zhang Zhizhen (second round)

• # 🇫🇷 Grégoire Barrère (first round)

• # Tim van Rijthoven (first round)

• # 🇨🇿 Tomáš Macháč (first round)

• # Nicolás Jarry (first round)

• # 🇪🇸 Fernando Verdasco (first round)