2022 Zadar Open – Singles

Nikola Milojević was the defending champion but lost in the first round to Eduard Esteve Lobato.

Flavio Cobolli won the title after defeating Daniel Michalski 6–4, 6–2 in the final.

Seeds
• # 🇮🇹 Gianluca Mager (first round)

• # 🇷🇸 Nikola Milojević (first round)

• # 🇸🇰 Andrej Martin (second round)

• # 🇨🇿 Zdeněk Kolář (first round)

• # 🇮🇹 Franco Agamenone (first round)

• # 🇮🇹 Flavio Cobolli (champion)

• # 🇧🇬 Dimitar Kuzmanov (first round)

• # 🇫🇷 Manuel Guinard (semifinals)