2024 Sardegna Open – Singles

Ugo Humbert was the defending champion but didn't defend his title as he was still competing in the Madrid Masters tournament.

Mariano Navone won the title after defeating Lorenzo Musetti 7–5, 6–1 in the final.

Seeds
The top four seeds received a bye into the second round. • # 🇺🇸 Frances Tiafoe (second round)

• # 🇮🇹 Lorenzo Musetti (final)

• # 🇦🇷 Mariano Navone (champion)

• # 🇺🇸 Christopher Eubanks (second round)

• # 🇮🇹 Lorenzo Sonego (second round)

• # 🇭🇺 Márton Fucsovics (quarterfinals, withdrew)

• # Nuno Borges (quarterfinals)

• # 🇮🇹 Luciano Darderi (semifinals)