5'-Deoxy-5'-fluoroadenosine

5′-Deoxy-5′-fluoroadenosine is the first step in the biosynthesis of organic fluorides. It is synthesized by the fluorinase catalyzed addition of a fluoride ion to S-adenosyl- L -methionine, releasing L -methionine as a by product. Purine nucleoside phosphorylase mediates a phosphorolytic cleavage of the adenine base to generate 5-fluoro-5-deoxy- D -ribose-1-phosphate.