ACP-SH:acetate ligase

Acetate—[acyl-carrier protein] ligase (, HS-acyl-carrier protein:acetate ligase, [acyl-carrier protein]:acetate ligase, MadH) is an enzyme with systematic name acetate:(acyl-carrier-protein) ligase (AMP-forming). This enzyme catalyses the following chemical reaction


 * ATP + acetate + an [acyl-carrier protein] $$\rightleftharpoons$$ AMP + diphosphate + an acetyl-[acyl-carrier protein]

This enzyme, from the anaerobic bacterium Malonomonas rubra, is a component of the multienzyme complex EC 4.1.1.89, biotin-dependent malonate decarboxylase.