AKAP8

A-kinase anchor protein 8 is an enzyme that, in humans, is encoded by the AKAP8 gene.

Function
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining it to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is redistributed to distinct locations during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.

Interactions
AKAP8 has been demonstrated to interact with:
 * Cyclin D3
 * DDX5,
 * MCM2,
 * MYCBP, and
 * PRKAR2A.