Acetylglutamate kinase

In enzymology, an acetylglutamate kinase is an enzyme that catalyzes the chemical reaction:


 * ATP + N-acetyl-L-glutamate $$\rightleftharpoons$$ ADP + N-acetyl-L-glutamyl 5-phosphate

Thus, the two substrates of this enzyme are ATP and N-acetyl-L-glutamate, whereas its two products are ADP and N-acetyl-L-glutamyl 5-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. This enzyme participates in urea cycle and metabolism of amino groups.

Nomenclature
The systematic name of this enzyme class is ATP:N-acetyl-L-glutamate 5-phosphotransferase. Other names in common use include:
 * N-acetylglutamate 5-phosphotransferase,
 * acetylglutamate phosphokinase,
 * N-acetylglutamate phosphokinase,
 * N-acetylglutamate kinase, and
 * N-acetylglutamic 5-phosphotransferase.

Structural studies
As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , and.