Alpha-glucuronidase

For beta-glucuronidase, see Beta-glucuronidase

In enzymology, an alpha-glucuronidase is an enzyme that catalyzes the chemical reaction


 * an alpha-D-glucuronoside + H2O $$\rightleftharpoons$$ an alcohol + D-glucuronate

Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate.

This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase.

Structural studies
As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , , and.