Athletics at the 2012 Summer Paralympics T/F42–46

Athletics events at the 2012 Summer Paralympics were held in the Olympic Stadium and in The Mall in London, United Kingdom, from 31 August to 9 September 2012. 31 events were staged for amputee athletes.

Classification
Athletes were given a classification depending on the type and extent of their disability. The classification system allowed athletes to compete against others with a similar level of function.

The athletics classifications are:
 * 11–13: Blind (11) and visually impaired (12, 13) athletes
 * 20: Athletes with an intellectual disability
 * 31–38: Athletes with cerebral palsy
 * 40: Les Autres (others) (including people with dwarfism)
 * 42–46: Amputees
 * 51–58: Athletes with a spinal cord disability

The class numbers were given prefixes of "T" and "F" for track and field events, respectively.