Bryan Grenfell

Bryan Thomas Grenfell (born 1954) is a British population biologist and the Kathryn Briger and Sarah Fenton Professor of Ecology and Evolutionary Biology and Public Affairs at the Princeton School of Public and International Affairs at Princeton University.

Education
Grenfell earned a Bachelor of Science degree with honours from Imperial College London, and DPhil in biology from the University of York in 1981.

Career and research
After his DPhil, Grenfell spent a post-doctoral period at Imperial College London, with Roy Anderson, before joining the faculty at the University of Sheffield. He moved to the University of Cambridge in 1990, to the Pennsylvania State University in 2004, and then to Princeton University in 2009. He has served as a member of the Board of Governors of the Wellcome Trust (2014–2021).

Grenfell's research focuses on the (often non-linear) dynamics and control of infectious diseases in humans and animals. He has used simple epidemiological models and time series analysis to interpret large spatio-temporal datasets, elucidating the spread through time and space of acute infectious pathogens, notably measles.

In 2004, Grenfell and colleagues coined the term phylodynamics to describe the interaction between pathogen evolutionary dynamics and the dynamics of epidemics. This concept has been widely applied since, for example, in discussing how pathogens evolve in response to host immunity.

Grenfell and collaborators have been extensively involved in analyzing the dynamics of the Severe Acute Respiratory Syndrome Coronavirus 2 pandemic that began in 2020. In particular, they have focused on the impact of immune life history on the future dynamics of the pandemic and the performance of vaccination strategies.

Awards and honours
In 1991 Grenfell was awarded a T.H. Huxley Medal from Imperial College London, and in 1995 the 1995 Scientific Medal of the Zoological Society of London. He was elected a Fellow of the Royal Society (FRS) in 2004. He has been a member of the American Academy of Arts and Sciences since 2006, and a Fellow of the American Association for the Advancement of Science since 2011. In 2008, he was awarded an Honorary Doctorate by the University of Sheffield. In 2022 he received the Kyoto Prize in Basic Sciences.