Butalamine

Butalamine is a vasodilator.

Synthesis
The reaction of benzamidoxime (1) with chlorine and subsequent reaction with cyanamide (3) gives 5-amino-3-phenyl-1,2,4-oxadiazole (4). Base catalyzed alkylation with dibutylaminoethyl chloride (5) completes the synthesis of butalamine (6).


 * Butalamine synthesis.svg