CDC5L

Cell division cycle 5-like protein is a protein that in humans is encoded by the CDC5L gene.

Function
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.

Interactions
CDC5L has been shown to interact with:


 * ASF/SF2,
 * BZW1,
 * CWC15,
 * DNA-PKcs,
 * DYNC1H1,
 * GCN1L1,
 * HSPA8,
 * ILF2,
 * PLRG1,
 * PPM1D,
 * PPP1CA,
 * PRPF19,
 * RBMX and
 * RPL12,
 * RPL13,
 * RPS16,
 * RPS25,
 * SF3A1,
 * SF3B1,
 * SF3B2,
 * SF3B4,
 * SFPQ,
 * SFRS2,
 * SNRPA1,
 * SNRPD3,
 * SRRM1,
 * Small nuclear ribonucleoprotein D1,
 * Small nuclear ribonucleoprotein D2,
 * Small nuclear ribonucleoprotein polypeptide A,
 * TOP2A, and
 * TTF2.