Carbamoyl-serine ammonia-lyase

The enzyme carbamoyl-serine ammonia-lyase (EC 4.3.1.13) catalyzes the chemical reaction


 * O-carbamoyl- L -serine + H2O = pyruvate + 2 NH3 + CO2 (overall reaction)
 * (1a) O-carbamoyl- L -serine = CO2 + NH3 + 2-aminoprop-2-enoate
 * (1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)
 * (1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous)

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is O-carbamoyl- L -serine ammonia-lyase (decarboxylating; pyruvate-forming). Other names in common use include O-carbamoyl- L -serine deaminase, carbamoylserine deaminase, and O-carbamoyl- L -serine ammonia-lyase (pyruvate-forming). It employs one cofactor, pyridoxal phosphate.