Carboxylate transporter

A carboxylate transporter is a membrane transport protein that transports carboxylate.

They are responsible for the reabsorption of filtered carboxylate in renal physiology, resulting in a 100% reabsorption in the proximal tubule.

In proximal tubule
In the renal proximal tubule, there are several kinds of carboxylate transporters in the apical membrane and the basolateral membrane.

Apical

 * Na-monocarboxylate cotransporter
 * 3Na-dicarboxylate cotransporter
 * 3Na-tricarboxylate cotransporter

Basolateral

 * H-monocarboxylate cotransporter
 * organic anion-dicarboxylate exchanger