Carotenoid isomerooxygenase

Carotenoid isomerooxygenase (, ninaB (gene)) is an enzyme with systematic name zeaxanthin:oxygen 15,15'-oxidoreductase (bond-cleaving, cis-isomerizing). This enzyme catalyses the following chemical reaction


 * zeaxanthin + O2 $$\rightleftharpoons$$ (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal

The enzyme from the moth Galleria mellonella and the fruit fly Drosophila melanogaster takes part in the synthesis of retinal.