Cathepsin A

Cathepsin A is an enzyme that is classified both as a cathepsin and a carboxypeptidase. In humans, it is encoded by the CTSA gene.

Function
This gene encodes a glycoprotein that associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high-molecular-weight multimers. The formation of this complex provides a protective role for stability and activity. It is protective for β-galactosidase and neuraminidase.

Clinical significance
Deficiencies in this gene are linked to multiple forms of galactosialidosis.

Interactions
Cathepsin A has been shown to interact with NEU1.