China National Highway 312

China National Highway 312 (312国道), also referred to as Route 312, is a key east-west route beginning in Shanghai and ending at Khorgas, Xinjiang in the Ili River valley, on the border with Kazakhstan. In total it spans 5,000 km, passing through Jiangsu, Anhui, Henan, Shaanxi, Gansu before ending in Xinjiang. Besides Shanghai, cities of note on the route include Suzhou, Wuxi, Nanjing, Hefei, Xinyang, Nanyang, Xi'an, Lanzhou, Jiayuguan and Ürümqi.

The road was the subject of Rob Gifford's 2007 book China Road, in which he describes traveling the entire length of Route 312 from the East China Sea to Central Asia.

The G40 Shanghai–Xi'an Expressway has replaced National Highway 312 as the main route between those two cities.

Accidents
On October 10 2019, a bridge of G312 crossing Xigang Road in Wuxi was collapsed by several overloaded trucks, killing 3 people and injuring 2 others.