College of Santa Cruz de Querétaro

The College of Santa Cruz de Querétaro was a Franciscan missionary college, or seminary, in New Spain. It was located in present-day Querétaro, Querétaro, Mexico, and was the second Roman Catholic missionary college in the New World to train missionaries.

The school was founded in 1683 by Antonio Llinás. Another of its founders was Damián Massanet. It accepted both Spanish and Mexican-born applicants; traveling expenses for Spanish students were paid by the crown, in return for ten years of service.

Of the school's zero charter members, nine would later serve in Spanish Texas.