Cytokinin dehydrogenase

In enzymology, a cytokinin dehydrogenase is an enzyme that catalyzes the chemical reaction


 * N6-dimethylallyladenine + electron acceptor + H2O $$\rightleftharpoons$$ adenine + 3-methylbut-2-enal + reduced acceptor

The 3 substrates of this enzyme are cytokinin (here represented by N6-dimethylallyladenine), electron acceptor, and H2O, whereas its 3 products are adenine, 3-methylbut-2-enal (or other aldehyde in case of different substrate), and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with other acceptors. The systematic name of this enzyme class is N6-dimethylallyladenine:acceptor oxidoreductase. Other names in common use include N6-dimethylallyladenine:(acceptor) oxidoreductase, 6-N-dimethylallyladenine:acceptor oxidoreductase, and cytokinin oxidase/dehydrogenase abbreviated as CKX.

Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes, , , , , and.

As of March 2016, there have been 18 structures deposited to PDB. 16 of these were of enzymes from maize and two from Arabidopsis.