Edward Holmes

Edward Holmes may refer to:


 * Edward Holmes (architect) (1832–1909), English architect
 * Edward Holmes (field hockey) (1880–1924), Irish field hockey player and Olympic medalist
 * Edward Holmes (musicologist) (1797–1859), English musicologist and music critic
 * Edward Lorenzo Holmes (1828–1900), American ophthalmologist
 * Edward C. Holmes (born 1965), British evolutionary biologist and virologist
 * Edward Carleton Holmes (1843–1932), one of the solicitors who drew up the first rules of Rugby Football Union
 * Edward Morell Holmes (1843–1930), British botanist, curator and lecturer
 * Lefty Holmes (nicknamed Eddie; 1907–1987), American baseball pitcher