Fox 21

Fox 21 may refer to:

Television stations in the United States:
 * WHNS Greenville, South Carolina
 * WFXR Roanoke, Virginia (as "Fox 21/27")
 * KXRM-TV Colorado Springs, Colorado
 * KQDS-TV Duluth, Minnesota
 * WBOC-DT2, Salisbury, Maryland

Other uses:
 * Fox 21 Television Studios, a unit of 20th Television